
How Long Do Anti-Wrinkle Injections Last? A Complete Timeline & Maintenance Guide
Anti-wrinkle injections are a cornerstone of modern aesthetic medicine, celebrated for their ability to smooth fine lines and restore a youthful…
Anti-wrinkle injections · Chiswick and Covent Garden
A targeted, refined treatment that softens vertical frown lines while maintaining facial harmony and expression.
5.0on Google · Read reviewsDr Harry JamesEvery treatment, personally

In short
Frown line treatment at Dr Harry Clinic, Chiswick and Covent Garden. Treats vertical glabellar lines at their muscular origin. Visible softening within 3 to 5 days, full effect in 10 to 14 days. Guide price from £200. Every treatment is carried out personally by Dr Harry James, MBChB PGDip (CAIT), GMC 7528423, at a CQC registered clinic.
At a glance
Treats vertical glabellar lines at their muscular origin
Prevents deepening by relaxing overactive muscles
Maintains natural brow positioning and symmetry
Visible softening within 3 to 5 days, full effect in 10 to 14 days
From £200 1 area · £280 two · £330 three
Dr Harry James
MBChB PGDip (CAIT), GMC 7528423
£75, book online
Reviews
★★★★★
I went to Dr Harry Clinic after both a recommendation and doing a lot of research, as this was my first anti-wrinkle injection treatment and choosing someone I truly trusted was really important to me. From the moment I arrived, Dr. Harry immediately made me feel at ease. He was so lovely, professional, and took the time to explain everything in detail. Most importantly, he really listened to what I wanted - especially my preference for a very natural look. Two weeks later, I had my complimentary follow-up appointment and I was already so happy with the results. At the follow-up, Harry was an absolute perfectionist, carefully assessing everything to ensure it was as balanced and natural as possible, with a small top-up where needed. Overall, my experience exceeded all expectations. If it’s your first time having treatment, or you’re looking for a new injector, I genuinely cannot recommend Dr Harry Clinic enough. One of the best decisions I’ve made.
YYasemin AksoyChiswick · via Google
★★★★★
Dr Harry is absolutely amazing, I can’t recommend him enough. I had my usual skin maintenance treatments yesterday, and for the first time I decided to try a lip booster. Harry was so informative, knowledgeable, and reassuring throughout, and he made me feel completely at ease. I was originally offered standard lip filler, but as I’m in my 60s I wanted something more subtle and natural-looking, the lip booster felt like the perfect choice. I left the clinic with only a little swelling (nothing too bad at all) and my lips already look healthier, more youthful, and beautifully natural. I’m genuinely thrilled with the result and can’t thank him enough. Five-star-plus treatment every time. His prices are very reasonable, and his manner with patients is kind, professional, and wonderful. I’m already looking forward to my next appointment, even if I have to wait a few months because the results last so well. Thank you Dr. Harry ❤️
IIvana SwanCovent Garden · via Google
★★★★★
Dr. Harry is incredibly knowledgeable and really takes his time to talk you through everything, answer any questions, and ensure you’re comfortable throughout the whole appointment. I never felt rushed, and he explained the treatment and expected results clearly, which made me feel really confident in the process. I’m so pleased with my results and wouldn’t hesitate to recommend him.
NNatasha-LaraChiswick · via Google
★★★★★
Great experience for an ultrasound-guided filler dissolution treatment. Dr Harry was very patient, caring and professional. I really appreciated the thorough consultation and felt well looked after throughout the treatment. Very happy with the results!
KKasey SongCovent Garden · via Google
★★★★★
I visited Dr Harry after having my lips done by a few, other practitioners and my experience was positively incomparable. Harry was extremely thorough with his questioning, support and actual practice, I felt reassured and at ease, alike did my Mum, at the hands of Harry. I had 0.6ml of lip filler and was extremely impressed that he reevaluated my lips afterwards, adding in the remaining filler into specific areas. I did not have 1 single bruise, despite coming up black and blue in the past, and my lips are the most symmetrical they have ever looked. 1 million percent the best investment I have made to my face and I would never recommend going to anybody else! I visited the Chiswick clinic and it was beautiful🫶🏼 thank you Harry
EEmmaChiswick · via Google
★★★★★
I went to Dr Harry Clinic after both a recommendation and doing a lot of research, as this was my first anti-wrinkle injection treatment and choosing someone I truly trusted was really important to me. From the moment I arrived, Dr. Harry immediately made me feel at ease. He was so lovely, professional, and took the time to explain everything in detail. Most importantly, he really listened to what I wanted - especially my preference for a very natural look. Two weeks later, I had my complimentary follow-up appointment and I was already so happy with the results. At the follow-up, Harry was an absolute perfectionist, carefully assessing everything to ensure it was as balanced and natural as possible, with a small top-up where needed. Overall, my experience exceeded all expectations. If it’s your first time having treatment, or you’re looking for a new injector, I genuinely cannot recommend Dr Harry Clinic enough. One of the best decisions I’ve made.
YYasemin AksoyChiswick · via Google
★★★★★
Dr Harry is absolutely amazing, I can’t recommend him enough. I had my usual skin maintenance treatments yesterday, and for the first time I decided to try a lip booster. Harry was so informative, knowledgeable, and reassuring throughout, and he made me feel completely at ease. I was originally offered standard lip filler, but as I’m in my 60s I wanted something more subtle and natural-looking, the lip booster felt like the perfect choice. I left the clinic with only a little swelling (nothing too bad at all) and my lips already look healthier, more youthful, and beautifully natural. I’m genuinely thrilled with the result and can’t thank him enough. Five-star-plus treatment every time. His prices are very reasonable, and his manner with patients is kind, professional, and wonderful. I’m already looking forward to my next appointment, even if I have to wait a few months because the results last so well. Thank you Dr. Harry ❤️
IIvana SwanCovent Garden · via Google
★★★★★
I visited Dr Harry after having my lips done by a few, other practitioners and my experience was positively incomparable. Harry was extremely thorough with his questioning, support and actual practice, I felt reassured and at ease, alike did my Mum, at the hands of Harry. I had 0.6ml of lip filler and was extremely impressed that he reevaluated my lips afterwards, adding in the remaining filler into specific areas. I did not have 1 single bruise, despite coming up black and blue in the past, and my lips are the most symmetrical they have ever looked. 1 million percent the best investment I have made to my face and I would never recommend going to anybody else! I visited the Chiswick clinic and it was beautiful🫶🏼 thank you Harry
EEmmaChiswick · via Google
Frown lines, medically known as glabellar lines, are the vertical wrinkles that develop between the eyebrows as a result of repeated muscle contractions when concentrating, squinting, or expressing concern.
These lines are among the most common concerns addressed with anti-wrinkle injections and often the first area patients choose to treat.
The development of frown lines follows a predictable pattern, beginning as dynamic wrinkles that appear only during facial expressions and gradually becoming static lines that remain visible even when the face is at rest.
This progression makes early intervention particularly beneficial, as treating dynamic lines prevents them from becoming permanently etched into the skin.
Dr Harry’s expertise in frown line treatment stems from his comprehensive understanding of the complex muscle interactions in the glabellar region and his experience as a trainer in aesthetic medicine.
This knowledge ensures that treatments not only smooth existing lines but also prevent future development whilst maintaining natural facial expressions.



The glabellar region includes the corrugator supercilii and procerus muscles, which pull the eyebrows inward and downward. These movements are central to expressive function but, over time, contribute to deep line formation. Treatment must also consider nearby structures, including the frontalis and orbicularis oculi, to preserve facial harmony and avoid complications. A clear understanding of how these muscles interact is key to achieving natural results without affecting surrounding areas.
Treatment begins with a comprehensive facial assessment. Dr Harry examines the strength, depth, and dynamic behaviour of the muscles involved, especially how the corrugator and procerus engage during expressions. Skin quality, brow position, and facial proportions are also reviewed. Subtle variations in anatomy are factored into every plan, ensuring treatment is adapted to your unique structure, not a one-size-fits-all approach.
Treatment begins with a comprehensive facial assessment. Dr Harry examines the strength, depth, and dynamic behaviour of the muscles involved, especially how the corrugator and procerus engage during expressions. Skin quality, brow position, and facial proportions are also reviewed. Subtle variations in anatomy are factored into every plan, ensuring treatment is adapted to your unique structure, not a one-size-fits-all approach.
Frown lines are typically treated with 3 to 5 injection points, precisely placed to relax the muscles causing the tension. Dr Harry uses advanced techniques including vector analysis and muscle mapping to ensure precision. Product is dosed strategically, not just to smooth lines, but to preserve expression and subtly lift the brow area where appropriate. Patients often describe the result as a softer, less tense appearance that still feels like them, just more open and relaxed.
This refined approach, combining anatomical detail with aesthetic finesse, ensures the outcome feels editorial, not artificial. Fine lines blur, brows appear slightly lifted, and expressions remain natural and dynamic.
For enhanced results, frown line treatment is often combined with forehead smoothing, crow’s feet correction, or strategic brow positioning. These areas work as an integrated unit, treating them together produces a more harmonious, refreshed look across the upper face.
The glabellar area contains key blood vessels and nerves, making precision essential. Dr Harry uses a combination of detailed mapping, sterile technique, and high-grade products such as Bocouture to ensure both safety and efficacy.
Anti-wrinkle injections are not suitable during pregnancy or breastfeeding and may not be appropriate for patients with certain medical conditions. During consultation, your full medical history is reviewed to confirm treatment suitability.
Comprehensive aftercare advice is always provided, and every step of the process, from assessment to aftercare, is designed to protect your wellbeing while delivering refined, confident results.

Meet Dr Harry James
Dr Harry James brings a wealth of experience and clinical precision to our London clinics. As a certified trainer in aesthetic medicine and a finalist in multiple national aesthetic award ceremonies, Dr Harry is recognised for his advanced techniques, patient-focused results, and commitment to setting high standards in non-surgical aesthetics.
His expertise extends beyond delivering treatment, he actively trains other practitioners and remains at the forefront of the field through continuous education and professional development.
Common questions
Frown line treatment typically takes 10-15 minutes, including consultation and injection time. The actual injection process takes only a few minutes, making it an ideal lunchtime treatment.
Most patients experience minimal discomfort during frown line treatment. Dr Harry uses ultra-fine needles and advanced injection techniques to minimise pain. Any discomfort is brief and well-tolerated.
Initial results typically become apparent within 3-5 days, with full effects visible within 10-14 days. The gradual onset ensures a natural transition to your improved appearance.
Yes, regular frown line treatment can help prevent the formation of deeper static lines by reducing the muscle activity that causes wrinkle formation. Early intervention is particularly effective for prevention.
Most patients benefit from treatment every 3-4 months to maintain optimal results. Dr Harry will recommend a personalised schedule based on your individual response and aesthetic goals.
Your visit
The same five steps for every patient, whatever you come in for.
Book online or call the clinic. A consultation is £75 and is redeemable against your treatment if you go ahead. Two to four weeks is the usual lead time.
A full medical history review, then a detailed assessment of your concerns and goals. Where the skin itself is the question, that includes an Observ 520x scan, which looks under the surface at sun damage, pigmentation and hydration. Unhurried, and with time to ask everything you want to ask. About the skin analysis
Dr Harry talks through the options and what each can and cannot do, then builds a personalised plan. Nothing is decided for you, and there is no obligation to treat on the day.
Carried out by Dr Harry James himself, never handed to whoever is free. You leave with written aftercare and a number to call if anything concerns you.
A follow up to assess how the treatment settled, monitor anything that needs watching and plan maintenance or next steps.
Where to have it
West London
Frown line treatment with Dr Harry James at our Chiswick clinic, W4. Six days a week, by appointment.
Dr Harry Clinic, Aesthetic Clinic in Chiswick300 Chiswick High Road, Chiswick, London W4 1NP
★★★★★ Rated 5.0 on Google
Central London
Frown line treatment with Dr Harry James at our Covent Garden clinic, WC2. Thursdays and Fridays, by appointment.
Dr Harry Clinic, Aesthetic Clinic in Covent GardenJubilee Hall, 30 The Piazza, Covent Garden, London WC2E 8BE
★★★★★ Rated 5.0 on Google
Frown line treatment is available at both clinics, at the same price and with the same practitioner: Dr Harry James carries out every treatment himself. Chiswick clinic · Covent Garden clinic.
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Ready when you are
A £75 consultation with Dr Harry James at Chiswick or Covent Garden, redeemable against your treatment if you go ahead. He assesses, explains what frown line treatment can and cannot do for you, and writes a plan. Nothing is decided for you on the day.
Chiswick, W4 and Covent Garden, WC2020 3633 8687