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Skin boosters · Chiswick and Covent Garden

Profhilo: Bio-remodelling for Skin Quality & Structure

Naturally restore skin firmness, hydration, and glow with Profhilo, the revolutionary injectable for full-face rejuvenation.

5.0on Google · Read reviews

Dr Harry JamesEvery treatment, personally

Editorial portrait for Profhilo, Dr Harry Clinic

In short

Profhilo at Dr Harry Clinic, Chiswick and Covent Garden. Deep hydration with high-purity hyaluronic acid. Stimulates collagen & elastin for skin tightening. Guide price £350. Every treatment is carried out personally by Dr Harry James, MBChB PGDip (CAIT), GMC 7528423, at a CQC registered clinic.

At a glance

What it does

Deep hydration with high-purity hyaluronic acid

How it works

Stimulates collagen & elastin for skin tightening

Benefit

Smooths fine lines and improves skin texture

Where it works

Works across face, neck, and hands

Guide price

£350 course of 3 £900

Practitioner

Dr Harry James
MBChB PGDip (CAIT), GMC 7528423

Clinics

Chiswick, W4 and Covent Garden, WC2

Consultation

£75, book online

On this plate

  • Profhilo Bio-remodelling
    Hydrates, firms, and revitalises skin. Stimulates collagen and elastin from within. Ideal for face, neck, hands, and décolletage.
  • Profhilo Bio-remodelling
    Restores firmness and elasticity by stimulating collagen and elastin in delicate neck skin. Improves hydration and texture, reducing crepiness and fine lines. Provides natural, gradual rejuvenation with results that develop over weeks and last up to 6 to 12 months.

Reviews

What patients say about Dr Harry.

5.0
★★★★★Google rating
  • ★★★★★

    Dr Harry is absolutely amazing, I can’t recommend him enough. I had my usual skin maintenance treatments yesterday, and for the first time I decided to try a lip booster. Harry was so informative, knowledgeable, and reassuring throughout, and he made me feel completely at ease. I was originally offered standard lip filler, but as I’m in my 60s I wanted something more subtle and natural-looking, the lip booster felt like the perfect choice. I left the clinic with only a little swelling (nothing too bad at all) and my lips already look healthier, more youthful, and beautifully natural. I’m genuinely thrilled with the result and can’t thank him enough. Five-star-plus treatment every time. His prices are very reasonable, and his manner with patients is kind, professional, and wonderful. I’m already looking forward to my next appointment, even if I have to wait a few months because the results last so well. Thank you Dr. Harry ❤️

    Ivana SwanCovent Garden · via Google

  • ★★★★★

    Dr. Harry is incredibly knowledgeable and really takes his time to talk you through everything, answer any questions, and ensure you’re comfortable throughout the whole appointment. I never felt rushed, and he explained the treatment and expected results clearly, which made me feel really confident in the process. I’m so pleased with my results and wouldn’t hesitate to recommend him.

    Natasha-LaraChiswick · via Google

  • ★★★★★

    Great experience for an ultrasound-guided filler dissolution treatment. Dr Harry was very patient, caring and professional. I really appreciated the thorough consultation and felt well looked after throughout the treatment. Very happy with the results!

    Kasey SongCovent Garden · via Google

  • ★★★★★

    I visited Dr Harry after having my lips done by a few, other practitioners and my experience was positively incomparable. Harry was extremely thorough with his questioning, support and actual practice, I felt reassured and at ease, alike did my Mum, at the hands of Harry. I had 0.6ml of lip filler and was extremely impressed that he reevaluated my lips afterwards, adding in the remaining filler into specific areas. I did not have 1 single bruise, despite coming up black and blue in the past, and my lips are the most symmetrical they have ever looked. 1 million percent the best investment I have made to my face and I would never recommend going to anybody else! I visited the Chiswick clinic and it was beautiful🫶🏼 thank you Harry

    EmmaChiswick · via Google

  • ★★★★★

    I went to Dr Harry Clinic after both a recommendation and doing a lot of research, as this was my first anti-wrinkle injection treatment and choosing someone I truly trusted was really important to me. From the moment I arrived, Dr. Harry immediately made me feel at ease. He was so lovely, professional, and took the time to explain everything in detail. Most importantly, he really listened to what I wanted - especially my preference for a very natural look. Two weeks later, I had my complimentary follow-up appointment and I was already so happy with the results. At the follow-up, Harry was an absolute perfectionist, carefully assessing everything to ensure it was as balanced and natural as possible, with a small top-up where needed. Overall, my experience exceeded all expectations. If it’s your first time having treatment, or you’re looking for a new injector, I genuinely cannot recommend Dr Harry Clinic enough. One of the best decisions I’ve made.

    Yasemin AksoyChiswick · via Google

  • ★★★★★

    Dr Harry is absolutely amazing, I can’t recommend him enough. I had my usual skin maintenance treatments yesterday, and for the first time I decided to try a lip booster. Harry was so informative, knowledgeable, and reassuring throughout, and he made me feel completely at ease. I was originally offered standard lip filler, but as I’m in my 60s I wanted something more subtle and natural-looking, the lip booster felt like the perfect choice. I left the clinic with only a little swelling (nothing too bad at all) and my lips already look healthier, more youthful, and beautifully natural. I’m genuinely thrilled with the result and can’t thank him enough. Five-star-plus treatment every time. His prices are very reasonable, and his manner with patients is kind, professional, and wonderful. I’m already looking forward to my next appointment, even if I have to wait a few months because the results last so well. Thank you Dr. Harry ❤️

    Ivana SwanCovent Garden · via Google

  • ★★★★★

    I visited Dr Harry after having my lips done by a few, other practitioners and my experience was positively incomparable. Harry was extremely thorough with his questioning, support and actual practice, I felt reassured and at ease, alike did my Mum, at the hands of Harry. I had 0.6ml of lip filler and was extremely impressed that he reevaluated my lips afterwards, adding in the remaining filler into specific areas. I did not have 1 single bruise, despite coming up black and blue in the past, and my lips are the most symmetrical they have ever looked. 1 million percent the best investment I have made to my face and I would never recommend going to anybody else! I visited the Chiswick clinic and it was beautiful🫶🏼 thank you Harry

    EmmaChiswick · via Google

  • ★★★★★

    I went to Dr Harry Clinic after both a recommendation and doing a lot of research, as this was my first anti-wrinkle injection treatment and choosing someone I truly trusted was really important to me. From the moment I arrived, Dr. Harry immediately made me feel at ease. He was so lovely, professional, and took the time to explain everything in detail. Most importantly, he really listened to what I wanted - especially my preference for a very natural look. Two weeks later, I had my complimentary follow-up appointment and I was already so happy with the results. At the follow-up, Harry was an absolute perfectionist, carefully assessing everything to ensure it was as balanced and natural as possible, with a small top-up where needed. Overall, my experience exceeded all expectations. If it’s your first time having treatment, or you’re looking for a new injector, I genuinely cannot recommend Dr Harry Clinic enough. One of the best decisions I’ve made.

    Yasemin AksoyChiswick · via Google

Understanding Profhilo

Profhilo is a revolutionary injectable treatment that represents a breakthrough in aesthetic medicine, offering unique bio-remodelling effects that improve skin quality from within. Unlike traditional dermal fillers, Profhilo works by stimulating the skin’s natural regenerative processes.

This innovative treatment contains one of the highest concentrations of hyaluronic acid available, formulated using patented NAHYCO technology that creates a unique hybrid complex. This formulation allows Profhilo to spread evenly through the skin, providing comprehensive bio-remodelling effects.

Dr Harry’s expertise in Profhilo treatment comes from his comprehensive understanding of skin biology and his experience as a trainer in aesthetic medicine. This knowledge ensures that treatments are optimised for maximum bio-remodelling benefits and natural-looking results.

Editorial portrait for Profhilo, Dr Harry Clinic
Dr Harry James seated at the consultation desk in three-quarter view, resting on folded hands.
Dr Harry James standing centred in the consultation room in landscape crop, shelving of ceramics behind.
  1. 01How Profhilo Works: The Science of Bio-Remodelling
  2. 02Where Profhilo Can Be Used
  3. 03Treatment Process and What to Expect
  4. 04Injection Techniques and Advanced Methodology
  5. 05Skin Benefits of Profhilo Treatment
  6. 06Combination Treatments and Integrated Planning
  7. 07Is Profhilo Right for You?

Profhilo Treatment Explained

01How Profhilo Works: The Science of Bio-Remodelling

Profhilo works through a biological process called bio-remodelling. This goes far beyond hydration, it actively stimulates four different types of collagen and elastin, creating a scaffold that supports skin structure and function.

As the product spreads under the skin, it triggers fibroblast activity, encourages tissue regeneration, and enhances dermal quality. These effects build gradually, with optimal results seen several weeks after treatment. Skin becomes:

  • Firmer and more elastic

  • Hydrated from within

  • Smoother in texture

  • Naturally more luminous

The process continues long after the injections are complete, offering ongoing improvement in skin health, resilience, and visible radiance.

02Where Profhilo Can Be Used

Profhilo is highly versatile and suitable for multiple areas that show signs of ageing or reduced skin quality. Dr Harry uses advanced techniques to tailor the treatment to each zone.

Face

The face is the most common area treated with Profhilo. It helps address fine lines, crepey skin, dull tone, and mild laxity, particularly in areas such as the cheeks, lower face, and jawline. Dr Harry uses a specialised injection method that ensures even distribution for optimal bio-remodelling.

Neck and Décolletage

These delicate areas are often the first to show signs of ageing due to thinner skin and sun exposure. Profhilo helps to tighten, smooth, and hydrate the neck and chest area without the need for lasers or surgery.

Hands

Ageing hands can benefit significantly from Profhilo. It improves thin, dry, or crepey skin, restoring a more youthful texture and suppleness. This is especially effective for patients seeking natural hand rejuvenation.

03Treatment Process and What to Expect

Profhilo is typically delivered as a course of two treatments, spaced four weeks apart. This phased approach allows the skin to respond biologically over time, producing more sustained and natural-looking results.

After the initial course, most patients will benefit from maintenance treatments every six to twelve months, depending on skin needs and ageing patterns.

Dr Harry provides a full consultation to determine the best schedule for you, factoring in skin condition, lifestyle, and other aesthetic goals. Each treatment is quick, with minimal discomfort and no downtime.

04Injection Techniques and Advanced Methodology

Profhilo is injected using a technique known as Bio-Aesthetic Points (BAP). These are specific anatomical sites that allow the product to diffuse evenly through the dermal layers, achieving optimal remodelling with minimal injections.

Dr Harry’s training in facial anatomy and injection science ensures each point is delivered with accuracy, safety, and minimal trauma to surrounding tissue. This advanced approach also:

  • Minimises swelling and bruising

  • Ensures maximum product efficacy

  • Supports consistent results across all treatment areas

In addition to the standard BAP technique, Dr Harry may adapt injection points based on individual facial structures and skin thickness, providing a truly bespoke treatment.

05Skin Benefits of Profhilo Treatment

Deep Hydration

Profhilo delivers exceptional hydration to the skin, improving both superficial and deep-layer moisture retention. Patients often notice a dewy, plumper look even within the first week.

Improved Elasticity and Firmness

Over time, the stimulation of collagen and elastin helps skin to tighten and regain its natural bounce, softening fine lines and lifting sagging areas without adding artificial volume.

Smoother Texture and Radiance

As the skin structure strengthens, texture becomes more refined. Profhilo creates a smoother surface, reduces crepey skin, and enhances overall skin glow.

06Combination Treatments and Integrated Planning

Profhilo works beautifully on its own, but it also pairs exceptionally well with other treatments. Dr Harry often incorporates Profhilo into larger treatment plans that may include:

  • Anti-wrinkle injections for expression lines

  • Dermal fillers for structural enhancement

  • Skin boosters for hydration layering

  • Laser or RF treatments for pigmentation or tightening

By integrating Profhilo into a wider aesthetic strategy, Dr Harry can help patients achieve results that are not only natural, but comprehensive and long-lasting.

The timing and sequencing of Profhilo alongside other treatments is essential. With his medical and aesthetic expertise, Dr Harry ensures each step is optimally coordinated for maximum benefit and minimal overlap.

07Is Profhilo Right for You?

Profhilo is ideal for anyone noticing early signs of ageing or reduced skin quality. You may be a good candidate if you:

  • Have dull, dehydrated, or crepey skin

  • Are seeing fine lines and a loss of elasticity

  • Want natural results without changing your facial structure

  • Are seeking a regenerative, preventative anti-ageing approach

Because Profhilo works with your own biology, it’s suitable for a wide age range and skin types. Dr Harry will assess your skin health and aesthetic goals before confirming if it’s the right treatment for you.

Dr Harry James, MBChB PGDip (CAIT), at Dr Harry Clinic
Dr Harry JamesMBChB PGDip (CAIT) · Aesthetic Doctor & Clinical Director

Meet Dr Harry James

Profhilo by a doctor who trains other practitioners.

Dr Harry James brings a wealth of experience and clinical precision to our London clinics. As a certified trainer in aesthetic medicine and a finalist in multiple national aesthetic award ceremonies, Dr Harry is recognised for his advanced techniques, patient-focused results, and commitment to setting high standards in non-surgical aesthetics.

His expertise extends beyond delivering treatment, he actively trains other practitioners and remains at the forefront of the field through continuous education and professional development.

  • Certified Aesthetic Medicine Trainer
  • Finalist in Multiple Aesthetic Award Ceremonies
  • Advanced Facial Injection Techniques Specialist
  • Medically Qualified with Extensive Postgraduate Training
  • Committed to Excellence in Patient Care & Safety
  • GMC registered, 7528423

Common questions

Profhilo Treatment FAQs

01How is Profhilo different from dermal fillers or skin boosters?

Profhilo is not a dermal filler or traditional skin booster, it’s a bio-remodeller. While fillers add volume and skin boosters hydrate superficially, Profhilo stimulates your own collagen and elastin production while deeply hydrating the skin. Its unique formulation spreads evenly under the skin, improving laxity, tone, and texture without altering facial structure.

Polynucleotides are the other treatment patients weigh Profhilo against, and they do a different job. Our guide to Profhilo vs polynucleotides explains which skin each one suits and when the two are combined.

02Is Profhilo suitable for younger patients or only mature skin?

Profhilo can benefit both younger and mature skin. For younger patients (late 20s to early 30s), it serves as a preventative treatment, improving skin hydration and delaying visible signs of ageing. For mature skin, it restores elasticity, firmness, and skin quality, making it an effective option at multiple stages of the skin ageing process.

03Does Profhilo build up over time with repeat treatments?

Yes. Profhilo’s bio-remodelling effects are cumulative, meaning that each treatment builds upon the last. Over time, the quality and integrity of your skin improves, often leading to longer intervals between treatments. Dr Harry will recommend a personalised maintenance plan, typically every 6 to 12 months, based on your skin’s needs and response.

04Will I look dramatically different after Profhilo?

No, Profhilo is designed to deliver subtle, natural-looking rejuvenation. You won’t look “done” or overfilled. Instead, you’ll notice healthier, smoother, more hydrated skin, with gradual improvements in firmness and radiance. Friends may comment that you look refreshed, but they won’t necessarily know why.

Your visit

From booking to follow up.

The same five steps for every patient, whatever you come in for.

  1. Book and arrive

    Book online or call the clinic. A consultation is £75 and is redeemable against your treatment if you go ahead. Two to four weeks is the usual lead time.

  2. Assessment

    A full medical history review, then a detailed assessment of your concerns and goals. Where the skin itself is the question, that includes an Observ 520x scan, which looks under the surface at sun damage, pigmentation and hydration. Unhurried, and with time to ask everything you want to ask. About the skin analysis

  3. Your plan

    Dr Harry talks through the options and what each can and cannot do, then builds a personalised plan. Nothing is decided for you, and there is no obligation to treat on the day.

  4. Treatment

    Carried out by Dr Harry James himself, never handed to whoever is free. You leave with written aftercare and a number to call if anything concerns you.

  5. Follow up

    A follow up to assess how the treatment settled, monitor anything that needs watching and plan maintenance or next steps.

Dr Harry explains

Watch: what is profhilo

A short explainer recorded in clinic by Dr Harry James.

Where to have it

Profhilo in Chiswick and Covent Garden

West London

Profhilo in Chiswick

Profhilo with Dr Harry James at our Chiswick clinic, W4. Six days a week, by appointment.

The consultation room at Dr Harry Clinic
Dr Harry Clinic, Aesthetic Clinic in Chiswick300 Chiswick High Road, Chiswick, London W4 1NP
Telephone020 3633 8687
HoursMonday to Saturday, 10am to 7pm, by appointment only
Getting hereChiswick Park station (District Line), 3 min walk. Bus routes 27, 237, 267, E3. Free parking on surrounding streets.

★★★★★ Rated 5.0 on Google

Central London

Profhilo in Covent Garden

Profhilo with Dr Harry James at our Covent Garden clinic, WC2. Thursdays and Fridays, by appointment.

Dr Harry James in the consultation room
Dr Harry Clinic, Aesthetic Clinic in Covent GardenJubilee Hall, 30 The Piazza, Covent Garden, London WC2E 8BE
Telephone020 3633 8687
HoursThursday and Friday, 10am to 7pm, by appointment only
Getting hereNearest: Covent Garden (Piccadilly Line).

★★★★★ Rated 5.0 on Google

Profhilo is available at both clinics, at the same price and with the same practitioner: Dr Harry James carries out every treatment himself. Chiswick clinic · Covent Garden clinic.

From the journal

Read before you book.

All articles
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Profhilo vs. Traditional Fillers: Understanding the Differences

Profhilo and traditional dermal fillers are both made from hyaluronic acid, and that is where the similarity ends. Profhilo is a bio-remodelling…

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Is Profhilo Safe? Side Effects, Risks and What Lowers Them

Profhilo has a strong safety record when it is assessed and given by a trained medical injector. What is normal, what is rare, who should avoid it…

Editorial portrait for Profhilo vs Polynucleotides: Which Skin Quality Treatment Do You Need?, Dr Harry Clinic

Collagen StimulatorsSkin Boosters

Profhilo vs Polynucleotides: Which Skin Quality Treatment Do You Need?

Profhilo hydrates and firms. Polynucleotides repair and rebuild. A Dr Harry Clinic guide to which skin quality treatment suits which skin, and when…

Close portrait of Dr Harry James on the clinic sofa, clinic scrubs embroidered with his name and qualifications.
Dr Harry JamesMBChB PGDip (CAIT)

Ready when you are

Book your Profhilo consultation.

A £75 consultation with Dr Harry James at Chiswick or Covent Garden, redeemable against your treatment if you go ahead. He assesses, explains what Profhilo can and cannot do for you, and writes a plan. Nothing is decided for you on the day.

Chiswick, W4 and Covent Garden, WC2020 3633 8687

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