
Profhilo vs. Traditional Fillers: Understanding the Differences
Profhilo and traditional dermal fillers are both made from hyaluronic acid, and that is where the similarity ends. Profhilo is a bio-remodelling…
Skin boosters · Chiswick and Covent Garden
Naturally restore skin firmness, hydration, and glow with Profhilo, the revolutionary injectable for full-face rejuvenation.
5.0on Google · Read reviewsDr Harry JamesEvery treatment, personally

In short
Profhilo at Dr Harry Clinic, Chiswick and Covent Garden. Deep hydration with high-purity hyaluronic acid. Stimulates collagen & elastin for skin tightening. Guide price £350. Every treatment is carried out personally by Dr Harry James, MBChB PGDip (CAIT), GMC 7528423, at a CQC registered clinic.
At a glance
Deep hydration with high-purity hyaluronic acid
Stimulates collagen & elastin for skin tightening
Smooths fine lines and improves skin texture
Works across face, neck, and hands
£350 course of 3 £900
Dr Harry James
MBChB PGDip (CAIT), GMC 7528423
£75, book online
On this plate
Reviews
★★★★★
Dr Harry is absolutely amazing, I can’t recommend him enough. I had my usual skin maintenance treatments yesterday, and for the first time I decided to try a lip booster. Harry was so informative, knowledgeable, and reassuring throughout, and he made me feel completely at ease. I was originally offered standard lip filler, but as I’m in my 60s I wanted something more subtle and natural-looking, the lip booster felt like the perfect choice. I left the clinic with only a little swelling (nothing too bad at all) and my lips already look healthier, more youthful, and beautifully natural. I’m genuinely thrilled with the result and can’t thank him enough. Five-star-plus treatment every time. His prices are very reasonable, and his manner with patients is kind, professional, and wonderful. I’m already looking forward to my next appointment, even if I have to wait a few months because the results last so well. Thank you Dr. Harry ❤️
IIvana SwanCovent Garden · via Google
★★★★★
Dr. Harry is incredibly knowledgeable and really takes his time to talk you through everything, answer any questions, and ensure you’re comfortable throughout the whole appointment. I never felt rushed, and he explained the treatment and expected results clearly, which made me feel really confident in the process. I’m so pleased with my results and wouldn’t hesitate to recommend him.
NNatasha-LaraChiswick · via Google
★★★★★
Great experience for an ultrasound-guided filler dissolution treatment. Dr Harry was very patient, caring and professional. I really appreciated the thorough consultation and felt well looked after throughout the treatment. Very happy with the results!
KKasey SongCovent Garden · via Google
★★★★★
I visited Dr Harry after having my lips done by a few, other practitioners and my experience was positively incomparable. Harry was extremely thorough with his questioning, support and actual practice, I felt reassured and at ease, alike did my Mum, at the hands of Harry. I had 0.6ml of lip filler and was extremely impressed that he reevaluated my lips afterwards, adding in the remaining filler into specific areas. I did not have 1 single bruise, despite coming up black and blue in the past, and my lips are the most symmetrical they have ever looked. 1 million percent the best investment I have made to my face and I would never recommend going to anybody else! I visited the Chiswick clinic and it was beautiful🫶🏼 thank you Harry
EEmmaChiswick · via Google
★★★★★
I went to Dr Harry Clinic after both a recommendation and doing a lot of research, as this was my first anti-wrinkle injection treatment and choosing someone I truly trusted was really important to me. From the moment I arrived, Dr. Harry immediately made me feel at ease. He was so lovely, professional, and took the time to explain everything in detail. Most importantly, he really listened to what I wanted - especially my preference for a very natural look. Two weeks later, I had my complimentary follow-up appointment and I was already so happy with the results. At the follow-up, Harry was an absolute perfectionist, carefully assessing everything to ensure it was as balanced and natural as possible, with a small top-up where needed. Overall, my experience exceeded all expectations. If it’s your first time having treatment, or you’re looking for a new injector, I genuinely cannot recommend Dr Harry Clinic enough. One of the best decisions I’ve made.
YYasemin AksoyChiswick · via Google
★★★★★
Dr Harry is absolutely amazing, I can’t recommend him enough. I had my usual skin maintenance treatments yesterday, and for the first time I decided to try a lip booster. Harry was so informative, knowledgeable, and reassuring throughout, and he made me feel completely at ease. I was originally offered standard lip filler, but as I’m in my 60s I wanted something more subtle and natural-looking, the lip booster felt like the perfect choice. I left the clinic with only a little swelling (nothing too bad at all) and my lips already look healthier, more youthful, and beautifully natural. I’m genuinely thrilled with the result and can’t thank him enough. Five-star-plus treatment every time. His prices are very reasonable, and his manner with patients is kind, professional, and wonderful. I’m already looking forward to my next appointment, even if I have to wait a few months because the results last so well. Thank you Dr. Harry ❤️
IIvana SwanCovent Garden · via Google
★★★★★
I visited Dr Harry after having my lips done by a few, other practitioners and my experience was positively incomparable. Harry was extremely thorough with his questioning, support and actual practice, I felt reassured and at ease, alike did my Mum, at the hands of Harry. I had 0.6ml of lip filler and was extremely impressed that he reevaluated my lips afterwards, adding in the remaining filler into specific areas. I did not have 1 single bruise, despite coming up black and blue in the past, and my lips are the most symmetrical they have ever looked. 1 million percent the best investment I have made to my face and I would never recommend going to anybody else! I visited the Chiswick clinic and it was beautiful🫶🏼 thank you Harry
EEmmaChiswick · via Google
★★★★★
I went to Dr Harry Clinic after both a recommendation and doing a lot of research, as this was my first anti-wrinkle injection treatment and choosing someone I truly trusted was really important to me. From the moment I arrived, Dr. Harry immediately made me feel at ease. He was so lovely, professional, and took the time to explain everything in detail. Most importantly, he really listened to what I wanted - especially my preference for a very natural look. Two weeks later, I had my complimentary follow-up appointment and I was already so happy with the results. At the follow-up, Harry was an absolute perfectionist, carefully assessing everything to ensure it was as balanced and natural as possible, with a small top-up where needed. Overall, my experience exceeded all expectations. If it’s your first time having treatment, or you’re looking for a new injector, I genuinely cannot recommend Dr Harry Clinic enough. One of the best decisions I’ve made.
YYasemin AksoyChiswick · via Google
Profhilo is a revolutionary injectable treatment that represents a breakthrough in aesthetic medicine, offering unique bio-remodelling effects that improve skin quality from within. Unlike traditional dermal fillers, Profhilo works by stimulating the skin’s natural regenerative processes.
This innovative treatment contains one of the highest concentrations of hyaluronic acid available, formulated using patented NAHYCO technology that creates a unique hybrid complex. This formulation allows Profhilo to spread evenly through the skin, providing comprehensive bio-remodelling effects.
Dr Harry’s expertise in Profhilo treatment comes from his comprehensive understanding of skin biology and his experience as a trainer in aesthetic medicine. This knowledge ensures that treatments are optimised for maximum bio-remodelling benefits and natural-looking results.



Profhilo works through a biological process called bio-remodelling. This goes far beyond hydration, it actively stimulates four different types of collagen and elastin, creating a scaffold that supports skin structure and function.
As the product spreads under the skin, it triggers fibroblast activity, encourages tissue regeneration, and enhances dermal quality. These effects build gradually, with optimal results seen several weeks after treatment. Skin becomes:
Firmer and more elastic
Hydrated from within
Smoother in texture
Naturally more luminous
The process continues long after the injections are complete, offering ongoing improvement in skin health, resilience, and visible radiance.
Profhilo is highly versatile and suitable for multiple areas that show signs of ageing or reduced skin quality. Dr Harry uses advanced techniques to tailor the treatment to each zone.
The face is the most common area treated with Profhilo. It helps address fine lines, crepey skin, dull tone, and mild laxity, particularly in areas such as the cheeks, lower face, and jawline. Dr Harry uses a specialised injection method that ensures even distribution for optimal bio-remodelling.
These delicate areas are often the first to show signs of ageing due to thinner skin and sun exposure. Profhilo helps to tighten, smooth, and hydrate the neck and chest area without the need for lasers or surgery.
Ageing hands can benefit significantly from Profhilo. It improves thin, dry, or crepey skin, restoring a more youthful texture and suppleness. This is especially effective for patients seeking natural hand rejuvenation.
Profhilo is typically delivered as a course of two treatments, spaced four weeks apart. This phased approach allows the skin to respond biologically over time, producing more sustained and natural-looking results.
After the initial course, most patients will benefit from maintenance treatments every six to twelve months, depending on skin needs and ageing patterns.
Dr Harry provides a full consultation to determine the best schedule for you, factoring in skin condition, lifestyle, and other aesthetic goals. Each treatment is quick, with minimal discomfort and no downtime.
Profhilo is injected using a technique known as Bio-Aesthetic Points (BAP). These are specific anatomical sites that allow the product to diffuse evenly through the dermal layers, achieving optimal remodelling with minimal injections.
Dr Harry’s training in facial anatomy and injection science ensures each point is delivered with accuracy, safety, and minimal trauma to surrounding tissue. This advanced approach also:
Minimises swelling and bruising
Ensures maximum product efficacy
Supports consistent results across all treatment areas
In addition to the standard BAP technique, Dr Harry may adapt injection points based on individual facial structures and skin thickness, providing a truly bespoke treatment.
Profhilo delivers exceptional hydration to the skin, improving both superficial and deep-layer moisture retention. Patients often notice a dewy, plumper look even within the first week.
Over time, the stimulation of collagen and elastin helps skin to tighten and regain its natural bounce, softening fine lines and lifting sagging areas without adding artificial volume.
As the skin structure strengthens, texture becomes more refined. Profhilo creates a smoother surface, reduces crepey skin, and enhances overall skin glow.
Profhilo works beautifully on its own, but it also pairs exceptionally well with other treatments. Dr Harry often incorporates Profhilo into larger treatment plans that may include:
Anti-wrinkle injections for expression lines
Dermal fillers for structural enhancement
Skin boosters for hydration layering
Laser or RF treatments for pigmentation or tightening
By integrating Profhilo into a wider aesthetic strategy, Dr Harry can help patients achieve results that are not only natural, but comprehensive and long-lasting.
The timing and sequencing of Profhilo alongside other treatments is essential. With his medical and aesthetic expertise, Dr Harry ensures each step is optimally coordinated for maximum benefit and minimal overlap.
Profhilo is ideal for anyone noticing early signs of ageing or reduced skin quality. You may be a good candidate if you:
Have dull, dehydrated, or crepey skin
Are seeing fine lines and a loss of elasticity
Want natural results without changing your facial structure
Are seeking a regenerative, preventative anti-ageing approach
Because Profhilo works with your own biology, it’s suitable for a wide age range and skin types. Dr Harry will assess your skin health and aesthetic goals before confirming if it’s the right treatment for you.

Meet Dr Harry James
Dr Harry James brings a wealth of experience and clinical precision to our London clinics. As a certified trainer in aesthetic medicine and a finalist in multiple national aesthetic award ceremonies, Dr Harry is recognised for his advanced techniques, patient-focused results, and commitment to setting high standards in non-surgical aesthetics.
His expertise extends beyond delivering treatment, he actively trains other practitioners and remains at the forefront of the field through continuous education and professional development.
Common questions
Profhilo is not a dermal filler or traditional skin booster, it’s a bio-remodeller. While fillers add volume and skin boosters hydrate superficially, Profhilo stimulates your own collagen and elastin production while deeply hydrating the skin. Its unique formulation spreads evenly under the skin, improving laxity, tone, and texture without altering facial structure.
Polynucleotides are the other treatment patients weigh Profhilo against, and they do a different job. Our guide to Profhilo vs polynucleotides explains which skin each one suits and when the two are combined.
Profhilo can benefit both younger and mature skin. For younger patients (late 20s to early 30s), it serves as a preventative treatment, improving skin hydration and delaying visible signs of ageing. For mature skin, it restores elasticity, firmness, and skin quality, making it an effective option at multiple stages of the skin ageing process.
Yes. Profhilo’s bio-remodelling effects are cumulative, meaning that each treatment builds upon the last. Over time, the quality and integrity of your skin improves, often leading to longer intervals between treatments. Dr Harry will recommend a personalised maintenance plan, typically every 6 to 12 months, based on your skin’s needs and response.
No, Profhilo is designed to deliver subtle, natural-looking rejuvenation. You won’t look “done” or overfilled. Instead, you’ll notice healthier, smoother, more hydrated skin, with gradual improvements in firmness and radiance. Friends may comment that you look refreshed, but they won’t necessarily know why.
Your visit
The same five steps for every patient, whatever you come in for.
Book online or call the clinic. A consultation is £75 and is redeemable against your treatment if you go ahead. Two to four weeks is the usual lead time.
A full medical history review, then a detailed assessment of your concerns and goals. Where the skin itself is the question, that includes an Observ 520x scan, which looks under the surface at sun damage, pigmentation and hydration. Unhurried, and with time to ask everything you want to ask. About the skin analysis
Dr Harry talks through the options and what each can and cannot do, then builds a personalised plan. Nothing is decided for you, and there is no obligation to treat on the day.
Carried out by Dr Harry James himself, never handed to whoever is free. You leave with written aftercare and a number to call if anything concerns you.
A follow up to assess how the treatment settled, monitor anything that needs watching and plan maintenance or next steps.
Dr Harry explains
A short explainer recorded in clinic by Dr Harry James.
Where to have it
West London
Profhilo with Dr Harry James at our Chiswick clinic, W4. Six days a week, by appointment.
Dr Harry Clinic, Aesthetic Clinic in Chiswick300 Chiswick High Road, Chiswick, London W4 1NP
★★★★★ Rated 5.0 on Google
Profhilo is available at both clinics, at the same price and with the same practitioner: Dr Harry James carries out every treatment himself. Chiswick clinic · Covent Garden clinic.
From the journal

Profhilo and traditional dermal fillers are both made from hyaluronic acid, and that is where the similarity ends. Profhilo is a bio-remodelling…

Profhilo has a strong safety record when it is assessed and given by a trained medical injector. What is normal, what is rare, who should avoid it…

Profhilo hydrates and firms. Polynucleotides repair and rebuild. A Dr Harry Clinic guide to which skin quality treatment suits which skin, and when…

Ready when you are
A £75 consultation with Dr Harry James at Chiswick or Covent Garden, redeemable against your treatment if you go ahead. He assesses, explains what Profhilo can and cannot do for you, and writes a plan. Nothing is decided for you on the day.
Chiswick, W4 and Covent Garden, WC2020 3633 8687