
How Long Do Anti-Wrinkle Injections Last? A Complete Timeline & Maintenance Guide
Anti-wrinkle injections are a cornerstone of modern aesthetic medicine, celebrated for their ability to smooth fine lines and restore a youthful…
Anti-wrinkle injections · Chiswick and Covent Garden
A delicate, targeted treatment that smooths vertical lip lines for a softer, more youthful look, without freezing expression.
5.0on Google · Read reviewsDr Harry JamesEvery treatment, personally

In short
Smoker's lines treatment at Dr Harry Clinic, Chiswick and Covent Garden. Minimises fine vertical wrinkles above and around the lips. Visible smoothing within 5 to 7 days, lasting 3 to 4 months. Guide price from £200. Every treatment is carried out personally by Dr Harry James, MBChB PGDip (CAIT), GMC 7528423, at a CQC registered clinic.
At a glance
Minimises fine vertical wrinkles above and around the lips
Ideal for lip lines caused by expressions, smoking, or ageing
Maintains natural mouth movement and subtle expression
Visible smoothing within 5 to 7 days, lasting 3 to 4 months
From £200 1 area · £280 two · £330 three
Dr Harry James
MBChB PGDip (CAIT), GMC 7528423
£75, book online
Reviews
★★★★★
Dr Harry is absolutely amazing, I can’t recommend him enough. I had my usual skin maintenance treatments yesterday, and for the first time I decided to try a lip booster. Harry was so informative, knowledgeable, and reassuring throughout, and he made me feel completely at ease. I was originally offered standard lip filler, but as I’m in my 60s I wanted something more subtle and natural-looking, the lip booster felt like the perfect choice. I left the clinic with only a little swelling (nothing too bad at all) and my lips already look healthier, more youthful, and beautifully natural. I’m genuinely thrilled with the result and can’t thank him enough. Five-star-plus treatment every time. His prices are very reasonable, and his manner with patients is kind, professional, and wonderful. I’m already looking forward to my next appointment, even if I have to wait a few months because the results last so well. Thank you Dr. Harry ❤️
IIvana SwanCovent Garden · via Google
★★★★★
I visited Dr Harry after having my lips done by a few, other practitioners and my experience was positively incomparable. Harry was extremely thorough with his questioning, support and actual practice, I felt reassured and at ease, alike did my Mum, at the hands of Harry. I had 0.6ml of lip filler and was extremely impressed that he reevaluated my lips afterwards, adding in the remaining filler into specific areas. I did not have 1 single bruise, despite coming up black and blue in the past, and my lips are the most symmetrical they have ever looked. 1 million percent the best investment I have made to my face and I would never recommend going to anybody else! I visited the Chiswick clinic and it was beautiful🫶🏼 thank you Harry
EEmmaChiswick · via Google
★★★★★
Dr. Harry is incredibly knowledgeable and really takes his time to talk you through everything, answer any questions, and ensure you’re comfortable throughout the whole appointment. I never felt rushed, and he explained the treatment and expected results clearly, which made me feel really confident in the process. I’m so pleased with my results and wouldn’t hesitate to recommend him.
NNatasha-LaraChiswick · via Google
★★★★★
Great experience for an ultrasound-guided filler dissolution treatment. Dr Harry was very patient, caring and professional. I really appreciated the thorough consultation and felt well looked after throughout the treatment. Very happy with the results!
KKasey SongCovent Garden · via Google
★★★★★
I went to Dr Harry Clinic after both a recommendation and doing a lot of research, as this was my first anti-wrinkle injection treatment and choosing someone I truly trusted was really important to me. From the moment I arrived, Dr. Harry immediately made me feel at ease. He was so lovely, professional, and took the time to explain everything in detail. Most importantly, he really listened to what I wanted - especially my preference for a very natural look. Two weeks later, I had my complimentary follow-up appointment and I was already so happy with the results. At the follow-up, Harry was an absolute perfectionist, carefully assessing everything to ensure it was as balanced and natural as possible, with a small top-up where needed. Overall, my experience exceeded all expectations. If it’s your first time having treatment, or you’re looking for a new injector, I genuinely cannot recommend Dr Harry Clinic enough. One of the best decisions I’ve made.
YYasemin AksoyChiswick · via Google
★★★★★
Dr Harry is absolutely amazing, I can’t recommend him enough. I had my usual skin maintenance treatments yesterday, and for the first time I decided to try a lip booster. Harry was so informative, knowledgeable, and reassuring throughout, and he made me feel completely at ease. I was originally offered standard lip filler, but as I’m in my 60s I wanted something more subtle and natural-looking, the lip booster felt like the perfect choice. I left the clinic with only a little swelling (nothing too bad at all) and my lips already look healthier, more youthful, and beautifully natural. I’m genuinely thrilled with the result and can’t thank him enough. Five-star-plus treatment every time. His prices are very reasonable, and his manner with patients is kind, professional, and wonderful. I’m already looking forward to my next appointment, even if I have to wait a few months because the results last so well. Thank you Dr. Harry ❤️
IIvana SwanCovent Garden · via Google
★★★★★
I visited Dr Harry after having my lips done by a few, other practitioners and my experience was positively incomparable. Harry was extremely thorough with his questioning, support and actual practice, I felt reassured and at ease, alike did my Mum, at the hands of Harry. I had 0.6ml of lip filler and was extremely impressed that he reevaluated my lips afterwards, adding in the remaining filler into specific areas. I did not have 1 single bruise, despite coming up black and blue in the past, and my lips are the most symmetrical they have ever looked. 1 million percent the best investment I have made to my face and I would never recommend going to anybody else! I visited the Chiswick clinic and it was beautiful🫶🏼 thank you Harry
EEmmaChiswick · via Google
★★★★★
I went to Dr Harry Clinic after both a recommendation and doing a lot of research, as this was my first anti-wrinkle injection treatment and choosing someone I truly trusted was really important to me. From the moment I arrived, Dr. Harry immediately made me feel at ease. He was so lovely, professional, and took the time to explain everything in detail. Most importantly, he really listened to what I wanted - especially my preference for a very natural look. Two weeks later, I had my complimentary follow-up appointment and I was already so happy with the results. At the follow-up, Harry was an absolute perfectionist, carefully assessing everything to ensure it was as balanced and natural as possible, with a small top-up where needed. Overall, my experience exceeded all expectations. If it’s your first time having treatment, or you’re looking for a new injector, I genuinely cannot recommend Dr Harry Clinic enough. One of the best decisions I’ve made.
YYasemin AksoyChiswick · via Google
Smoker’s lines, also referred to as vertical lip lines or perioral wrinkles, are the fine creases that develop above the upper lip and, less commonly, below the lower lip. While often associated with smoking, they can appear in anyone due to repetitive lip movement, natural ageing, sun exposure, or collagen loss.
These lines tend to become more visible with facial expressions such as talking, sipping, or smiling, and may persist even at rest as the skin’s structure weakens. They can give the lips a pursed or aged appearance, even when other features remain smooth.
Anti-wrinkle injections work by relaxing the overactive orbicularis oris muscle, the circular muscle around the mouth, softening the creases and helping restore a smoother lip contour without adding volume or affecting function.



The orbicularis oris controls movement of the lips during speaking, drinking, kissing, and expression. Over time, its repetitive motion creates fine lines radiating outward from the lip border. Because the skin in this area is thin and constantly in motion, these lines can deepen quickly, particularly in patients with reduced skin elasticity.
Precision is essential when treating this area. The muscle is closely connected to surrounding structures, including those responsible for lip shape and speech articulation. A carefully placed dose relaxes unwanted tension while preserving natural motion, lip control, and speech.
The treatment process begins with an evaluation of the perioral region, assessing line depth, muscle strength, and how your lips move at rest and in expression. Smile pattern, speech habits, and lip shape are all considered to ensure treatment supports both aesthetics and function.
Small quantities of anti-wrinkle product are carefully injected into the upper (and occasionally lower) sections of the orbicularis oris. Injections are placed superficially and spaced evenly to minimise the appearance of vertical lines without compromising lip movement.
Precision and restraint are key. Over-treatment may lead to stiffness or difficulty articulating certain sounds, which is why doses are light and adapted to each individual’s needs.
Patients usually begin to notice softening within three to five days, with full results appearing by two weeks. Fine lines appear less etched, and lipstick bleed is often reduced. The lips look smoother and more defined, not frozen or overdone.
Movement remains natural, and results typically last around three to four months. With regular maintenance, the area can remain smoother long-term and may show a cumulative reduction in line severity over time.
Smoker’s line treatment is often combined with a lip flip or subtle filler to enhance the border and shape of the lips. Together, these treatments can define the vermilion edge, reduce creasing, and restore balance without excessive volume.
For deeper lines around the mouth or chin, this treatment can be paired with additional wrinkle-relaxing injections or dermal fillers in the nasolabial or marionette zones. This creates a smoother, more unified look across the lower third of the face.
Injections around the mouth must be performed with anatomical care. The muscles involved are active and finely tuned, responsible for essential actions like eating, speaking, and smiling. That’s why subtlety is essential.
Each treatment uses premium-grade products such as Bocouture by Merz and follows a careful injection protocol to ensure precision and safety. Aftercare is simple, with no downtime, and patients can resume normal activity immediately.
Results are reviewed to ensure natural movement is preserved while achieving the desired softening effect. Follow-up treatments can be scheduled for ongoing refinement and confidence in the outcome.

Meet Dr Harry James
Dr Harry James brings a wealth of experience and clinical precision to our London clinics. As a certified trainer in aesthetic medicine and a finalist in multiple national aesthetic award ceremonies, Dr Harry is recognised for his advanced techniques, patient-focused results, and commitment to setting high standards in non-surgical aesthetics.
His expertise extends beyond delivering treatment, he actively trains other practitioners and remains at the forefront of the field through continuous education and professional development.
Common questions
Smoker’s lines, also known as vertical lip lines or perioral lines, are fine wrinkles that develop above the upper lip. Although they’re often associated with smoking, they can appear in non-smokers due to natural ageing, repetitive lip movement (like sipping from straws or pursing the lips), sun damage, and collagen loss. Dr Harry treats these lines by gently relaxing the overactive muscles around the mouth, resulting in smoother skin and softer lip contours.
Anti-wrinkle injections work by temporarily relaxing the orbicularis oris muscle, the circular muscle around the mouth responsible for lip movement. By softening its activity, fine lines above the upper lip become less visible, especially when speaking or smiling. Dr Harry uses ultra-precise microdoses to reduce wrinkling while maintaining natural lip movement and expression.
Yes, when expertly administered, the treatment will not interfere with normal lip function. Because the area around the mouth is very dynamic, precision is essential. Dr Harry carefully adjusts dosage and injection placement to ensure your ability to speak, eat, and smile is preserved, while still delivering noticeable smoothing of upper lip lines.
You can expect visible results within 5 to 10 days, with full effect at around 2 weeks. The smoothing effect typically lasts for 3 to 4 months, depending on your muscle activity and metabolism. Regular maintenance can help reduce the depth of lines over time and prevent new ones from forming.
Your visit
The same five steps for every patient, whatever you come in for.
Book online or call the clinic. A consultation is £75 and is redeemable against your treatment if you go ahead. Two to four weeks is the usual lead time.
A full medical history review, then a detailed assessment of your concerns and goals. Where the skin itself is the question, that includes an Observ 520x scan, which looks under the surface at sun damage, pigmentation and hydration. Unhurried, and with time to ask everything you want to ask. About the skin analysis
Dr Harry talks through the options and what each can and cannot do, then builds a personalised plan. Nothing is decided for you, and there is no obligation to treat on the day.
Carried out by Dr Harry James himself, never handed to whoever is free. You leave with written aftercare and a number to call if anything concerns you.
A follow up to assess how the treatment settled, monitor anything that needs watching and plan maintenance or next steps.
Where to have it
West London
Smoker's lines treatment with Dr Harry James at our Chiswick clinic, W4. Six days a week, by appointment.
Dr Harry Clinic, Aesthetic Clinic in Chiswick300 Chiswick High Road, Chiswick, London W4 1NP
★★★★★ Rated 5.0 on Google
Central London
Smoker's lines treatment with Dr Harry James at our Covent Garden clinic, WC2. Thursdays and Fridays, by appointment.
Dr Harry Clinic, Aesthetic Clinic in Covent GardenJubilee Hall, 30 The Piazza, Covent Garden, London WC2E 8BE
★★★★★ Rated 5.0 on Google
Smoker's lines treatment is available at both clinics, at the same price and with the same practitioner: Dr Harry James carries out every treatment himself. Chiswick clinic · Covent Garden clinic.
From the journal

Anti-wrinkle injections are a cornerstone of modern aesthetic medicine, celebrated for their ability to smooth fine lines and restore a youthful…

Navigating the world of aesthetic treatments can be complex, especially when faced with popular and effective options like anti-wrinkle injections…

Making the decision to have your first anti-wrinkle treatment is a significant step. It’s normal to feel a mixture of excitement and apprehension…
More in this range

Ready when you are
A £75 consultation with Dr Harry James at Chiswick or Covent Garden, redeemable against your treatment if you go ahead. He assesses, explains what smoker's lines treatment can and cannot do for you, and writes a plan. Nothing is decided for you on the day.
Chiswick, W4 and Covent Garden, WC2020 3633 8687